• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Sorefanib promotes Hepatocellular carcinoma cells apoptosis bydownregulating AIB1 protein expression

Sorefanib promotes Hepatocellular carcinoma cells apoptosis bydownregulating AIB1 protein expression

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：ericli2009
【摘 要】
：
Sorafenib is an oral multi-kinase inhibitor and represents a major breakthrough in thetherapy of advanced hepatocellular carcinoma.However, the mechanisms of Sorafenibmediated-antitumor affects in HCC
【作 者】
：
李明 王薇 秦丽萍 陈文博 庄明强 莫萍丽 俞春东 
【机 构】
：
厦门大学生命科学学院
【出 处】
：
中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议
【发表日期】
：
2014年3期
【关键词】
：
Sorafenib AIB 1 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Sorafenib is an oral multi-kinase inhibitor and represents a major breakthrough in thetherapy of advanced hepatocellular carcinoma.However, the mechanisms of Sorafenibmediated-antitumor affects in HCC have not been fully elucidated.AIB1 is frequently overexpressedin human HCC tissues and promotes hepatocellular carcinoma progression.
其他文献
Structural Basis for Hydroxymethylcytosine Recognition by the SRADomain of UHRF2
Methylated cytosine of CpG dinucleotides in vertebrates may be oxidized by Tet proteins,a process that can lead to DNA demethylation.The predominant oxidation product, 5-hydroxymethylcytosine (5hmC),
会议
DNA hydroxymethylation SRA domain 5hmC recognition Epigentic regulation
RhoGDIβ switches cell fate between smooth muscle cell versus adipocyte via regulating actin filament
Mesenchymal stem cells can differentiation into multiple mesoderm cell types under differentinducing conditions and the inducers of the differentiation along one lineage oftenrepresses the differentia
会议
RhoGDIβ smooth muscle cells adipocytes Rac1 Mesenchymal stem cells
The contributions of Blood Biomarkers in clinical diagnosis in AcuteTrauma/Injury
Background: Acute trauma/injury is always fatal to the patients.So early diagnosis andtherapeutic plan are very important.Diagnosis relies on many methods, such as imagingtechniques, blood biomarkers,
会议
acute trauma injury biomarker
Polymorphisms of EPAS1 Gene Associations with High AltitudePolycythemia in Tibetans at the Qinghai-T
Objective To test the hypothesis that the polymorphisms in EPAS1 gene are assoeiatedwith the susceptibility to high altitude polycythemia (HAPC) in Tibetans at the Qinghai-Tibetan Plateau.Methods This
会议
EPAS1 High Altitude Polycythemia
Galangin suppresses proliferation of HepG2 cells via activatingTGF-□receptors/Smads pathways
Galangin can suppress the proliferation of HCC cells.In this study, we demonstrated thatgalangin induced autophagy by activating the TGF-βreceptors/Smads pathways.It stimulatedthe increases of TGF-βRI
会议
galangin autophagy Smad
Effects of Scutellarin against neurotoxicity induced by betaamyloidpeptide in human SH-SY5Y neurobla
Scutellarin (Scu) is the major active principle extracted from Herba Erigerontis (HE), aChinese herbal medicine derived from Erigeron breviscapus.The study is designed to investigatethe effects of Scu
会议
Herba Erigerontis SH-SY5Y cells Nicotinic acetylcholine receptor β-amyloidp epti
A novel pyrazolone-base derivative induces apoptosis in humanesophageal cells via reactive oxygen sp
Previous reports suggested that Pyrazolone complexes have strong bio-activity.Whereas,there is only scant the anti-tumor mechanism of pyrazolone-based metal complexes.Theinhibitory effect and possible
会议
Pyrazolone-base derivative Cadmium Eca-109 cells Apoptosis Mitochondrialp athway
Thiamine Deficiency Promotes T Cell Infiltration in ExperimentalAutoimmune Encephalomyelitis: the In
Multiple sclerosis (MS) is a complex multifactorial disease that results from the interplaybetween environmental factors and a susceptible genetic background.Experimentalautoimmune encephalomyelitis (
会议
Experimental Autoimmune Encephalomyelitis C-C Chemokine Ligand 2 T lymphocyte Th
Beta-Ecdysone Prevents Glucocorticoid-induced Bone Loss byPreserving Osteogenesis and Osteocyte Auto
Introduction.Achyranthes root (Niu xi) is one of the Chinese herbs often used to treat avariety of disorders such as low back pain, circulatory disorders and aging.Extracts ofachyranthes are found to
会议
Beta-Ecdysone Glucocorticoid Osteoporosis Autophagy
Effects of Kidney-Tonifying Recipe on Neural Cell Apoptosis andSpatial Learning & Memory of Aging Ra
Objective: To observe the effects of kidney-tonifying recipe-Zuogui Wan (左归丸) and Radix Rehmanniae Praeparata (熟地黄) on learning & memory ability and themRNA expressions of proBDNF, p75NTR, sortilin, c
会议
Ageing Rats Apoptosis Learning and Memory D-galactose