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  5. Fragment Ion Pairs Based Proteomics Search Algorithm for improving the Quantification Coverage of Is

Fragment Ion Pairs Based Proteomics Search Algorithm for improving the Quantification Coverage of Is

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：znzlwzkp
【摘 要】
：
Quantitative proteomics plays an important role in the comparison of biological systems.The incorporation of stable isotopes to achieve differentially labeled peptides allowing for a comparison of rel
【作 者】
：
Yichu Shan Shen Zhang Qi Wu Zhen Liang Lihua Zhang Yukui Zhang 
【机 构】
：
CAS Key Lab of Separation Sciences for Analytical Chemistry,National Chromatographic Research and An
【出 处】
：
第八届中国蛋白质组学大会
【发表日期】
：
2013年11期
【关键词】
：
Fragment ion pairs isobaric peptide termini labeling scoring algorithm coverage 
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Quantitative proteomics plays an important role in the comparison of biological systems.The incorporation of stable isotopes to achieve differentially labeled peptides allowing for a comparison of relative abundances is key in most mass spectrometry (MS)-based methods.Among which,quantification based on isobaric peptide termini labeling (IPTL) attracts more and more attention.
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