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Temperature-responsive double hydrophilic block copolymers (DHBCs) based on poly(oligo(ethylene glycol) methacrylate) (POEGMA) have attracted great interest because of adjustable LCST and excellent biocompatibility.Whats more,thermoresponsive DHBCs containing carbohydrate pendants have many practical advantages compared to POEGMA,and have a potential application as targeting drug-delivery system [1-2].