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5. The effect of noradrenaline and α1-adrenoceptors antagonists on the rat hepatic stellate cells

The effect of noradrenaline and α1-adrenoceptors antagonists on the rat hepatic stellate cells

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：lokimi

【摘 要】

：

Aim: To investigate the distribution and function of α1-adenoreceptor subtypes (α1-AR) in rat hepatic stellate cells (HSC-T6), and to investigate the effect of noradrenaline (NA) on the activation and

【作 者】

：

Ting-ting LIU Ti-long DING Yong MA Wei WEI 

【机 构】

：

Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory an

【出 处】

：

The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

：

2013年4期

【关键词】

：

hepatic stellate cells noradrenaline α1-adrenoceptors hepatic fibrosis 

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Aim: To investigate the distribution and function of α1-adenoreceptor subtypes (α1-AR) in rat hepatic stellate cells (HSC-T6), and to investigate the effect of noradrenaline (NA) on the activation and proliferation of HSC-T6 and on their synthesis capacity of extracellular matrix proteins (ECM).

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