Implication of H63D polymorphism of the HFE gene in aggressive cancers: a meta-analysis of 28 case-c

来源 :第十八届全国临床肿瘤学大会暨2015年CSCO学术年会 | 被引量 : 0次 | 上传用户:sven1989
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective: we performed this meta-analysis to summarize the effect of H63D variant on solid tumor incidence.Method: The PubMed and EMBASE databases were searched regarding the HFE H63D polymorphism associated with cancer risk.
其他文献
Objective: Hepatocellular carcinoma (HCC) is a lethal malignancy worldwide and lacking effective medication.Protein phosphatase magnesium-dependent 1δ (PPM1D) is a potential oncogene and promising pro
Objective: High serum albumin (ALB) and albumin/globulin ratio (AGR) have been reported to be associated with a favorable prognosis for several types of cancer.
Objective: B7-H3, a member from B7-family co-stimulatory ligands, plays an important role in adaptive immune responses.In addition, recent studies also demonstrated that B7-H3 could be highly expresse
Objective: This study was undertaken to evaluate the selective activation and targeted cell killing of AKR1C3-prodrug both in vitro and in vivo for liver cancer cells.
Objective: Epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors are useful in treating different advanced human cancers;however, their clinical efficacy varies.
Objective: For khead box protein C2 (FOXC2) plays a vital role in the carcinogenesis of some malignances.However, its clinicopathologic significance and prognostic value in colon cancer remain unclear
Objective: To explore the association between 5-FU-basedchemotherapy associated hyperglycemia and 5-year outcome of CRC patients.Method: A retrospective analysis was performed in this study to explore
The conventional strategy for cancer therapy offers limited control of specificity and efficacy, study on the molecular mechanism involved in tumor growth and angiogenesis provides novel targets and d
Objective: The aim of this study was to investigate the clinicopathological and prognostic relevance of metastasis associated with lysyl oxidase (LOX), vascular endothelial growth factor-A(VEGF-A), Hy
Objective: Hyperthermia induces cancer cellapoptosis, but its molecular mechanisms remain unclear.Here, we investigated the role of Survivin in hyperthermia induced apoptosis in esophageal cancer.