Grape Seed Extract Reduces Bleomycin-induced Pulmonary Fibrosis in Mice

来源 :2016年全国抗炎免疫药理学术会议 | 被引量 : 0次 | 上传用户：ZJWLMX

【摘要】

：

Aim: Idiopathic pulmonary fibrosis (IPF), the most prevalent idiopathic interstitial pneumonia, has a median survival of 3 to 5 years from diagnosis, but its etiology remains unknown.

【作者】

：

Qi Liu Ya-nan Liu ling-tian Ge Jun-xia Jiang Wei Zhao Yong-liang Jia Xin-wei Dong Yun Sun Qiang-min Xie

【机构】

：

Medical College of Yangzhou University, 11 Huaihai Road, Yangzhou 225001

【出处】

：

2016年全国抗炎免疫药理学术会议

【发表日期】

：

2016年11期

【关键词】

：

Grape Seed Extract Pulmonary fibrosis Bleomycin EMT

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Aim: Idiopathic pulmonary fibrosis (IPF), the most prevalent idiopathic interstitial pneumonia, has a median survival of 3 to 5 years from diagnosis, but its etiology remains unknown.

其他文献

Apabetalone, a BET bromodomain inhibitor specific for second bromodomains reactivates latent HIV-1 b

The persistence of latent HIV-1 reservoirs in resting memory CD4+T cells is a major barrier on the path to achieve a cure for HIV even though antiretroviral therapy (ART).

会议

精液等效地促进传播创始者和慢性控制者HIV-1的感染

大约有80％的HIV-1异性性传播是由单一的传播创始者(transmitted/founder,T/F)毒株所引起的.相比于慢性感染阶段的慢性控制者(chronic controls,CC) HIV-1,T/F毒株的感染性更强,整合了更多的糖蛋白,具有更少的N联接糖基化位点,更能高效地被树突状细胞捕获,且对IFN-α耐药性更强.

会议

FY-11 suppresses RANKL-induced osteoclast formation by attenuating NF-κB and the expression of DC-ST

Objective: Bone formation by osteoblasts and bone re sorption by osteoclasts contributes to the balance of bone remodelling.Most pathologic bone diseases are due to excess osteoclastic activity, leadi

会议

nitrobenzoyl sesquiterpenoidosteoclastRANKLNF-κBDC-STAMP

A novel DMARD, Iguratimod disrupts TGF-signaling in epithelial cells and attenuates bleomycin-induce

Objective: To determine the effect of iguratimod, a novel DMARD, on bleomycin-induced lung fibrosis and describe the underlying mechanisms.Methods: Mice were anaesthetized and then intratracheally inj

会议

Berberine inhibits NLRP3 inflammasome activation by triggering autophagy in adipose tissue macrophag

Aims: Insulin resistance, a hallmark of type 2 diabetes, is associated with obesity.Obesity gives rise to a state of chronic, low-grade inflammation that contributes to insulin resistance.Obese adipos

会议

黄芩素通过MD2/TLR4信号通路缓解LPS诱导的急性肺损伤

目的:探讨黄芩素(BAI)通过抑制髓样分化蛋白2(MD2) /Toll样受体4(TLR4)复合缓解脂多糖(LPS)诱导的炎症与急性肺损伤(ALI).方法:1.通过表面等离子体共振技术、分子对接、免疫荧光、免疫共沉淀、蛋白ELISA实验和氨基酸突变等方法来探究黄芩素和MD2的结合机制.

会议

急性肺损伤髓样分化蛋白2Toll样受体4黄芩素脂多糖

Effect of Soluble Epoxide Hydrolase Deficiency on Regulatory B Cells

Regulatory B cells (Breg) are immunosuppressive cells that protect immune responses that can result in uncontrolled inflammation.Multiple studies demonstrated that IL-10 is not just a maker for Breg i

会议

烟酸对血管内皮细胞NLRP3炎症小体活化的作用及机制研究

目的:研究烟酸对血管内皮细胞NLRP3炎症小体活化的影响及其作用机制.方法:体外培养血管内皮细胞,烟酸预处理后观察其对LPS/ATP诱导的血管内皮细胞NLRP3炎症小体活化的影响,同时观察烟酸对SIRT1表达的调控作用.

会议

烟酸NLRP3炎症小体SIRT1ROS

SIRT1 inhibition promotes atherosclerosis through impaired autophagy

SIRT1, a highly conserved NAD+-dependent protein deacetylase, plays a pivotal role in thepathogenesis and therapy of atherosclerosis.

会议

atherosclerosisSIRT1deacetylationautophagyAtg5

SIRT1 Inactivation Accelerates foam Cell Formation in Ox-LDL-treated Human THP-1 Cells and Promotes

Background: SIRT1, a highly conserved NAD+-dependent protein deacetylase, plays a pivotal role in caloric restriction on lifespan and metabolic pathways as well as in the regulation of pathogenesis an

会议

Grape Seed Extract Reduces Bleomycin-induced Pulmonary Fibrosis in Mice

与本文相关的学术论文