Protective effect of 5-aza-2'-deoxycytidine treatment on cigarette smoke-induced emphysema/chro

来源 :第十届中青年呼吸学者论坛 | 被引量 : 0次 | 上传用户：hhzzmm

【摘要】

：

In the present study, we explored the effects of demethylation on lung function, lung cell apoptosis and the cytochrome c oxidase (COX) activity in a cigarette smoke-induced emphysema/chronic obstruct

【作者】

：

ZHANG Hong-liang CHEN Ping ZENG Hui-hui ZHANG Yan PENG Hong CHEN Yan

【机构】

：

Emergency Department,Second Xiangya Hospital,Central South University,Changsha,Hunan 410011,China

【出处】

：

第十届中青年呼吸学者论坛

【发表日期】

：

2013年2期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

影像学发现肺部孤立小结节:宜严密随访

肺部孤立性结节(solitary pulmonary nodule,SPN)是指肺内直径≤3 cm的单个圆形、类圆形或形态不规则的局限性病灶,边界清楚,外周被含气肺组织包裹的影像学改变.需除外胸腔积液、空洞、肺不张、卫星病灶和肺门淋巴结肿大等.

会议

渗出液和漏出液的鉴别诊断

胸腔积液的形成是由于胸腔液体的入量多于出量造成的,其机制包括:肺毛细血管压增高(如充血性心力衰竭)、血管通透性增高(如肺炎)、胸腔内压力变小(如肺不张)、血浆胶体渗透压降低(如低蛋白血症)、胸膜通透性增高及淋巴液的循环受阻(如胸膜恶性肿瘤或感染)、隔下炎症(如肝脓肿)、以及胸导管破裂(如乳糜胸)等.

会议

中性粒细胞性哮喘:我们还需要知道得更多

全球哮喘防治指南(GINA)将哮喘定义为一种"慢性气道炎症性疾患".近年的研究都证实哮喘是一种有明显异质性(heterogeneity)的疾病.这种异质性使哮喘从气道炎症机制、病理生理和临床表现等方面都可以分为一些不同的表型(Phenotypes).

会议

特发性间质性肺炎新分类

国际上第一个关于特发性间质性肺炎(IIP)的专家共识是2002年由美国胸科学会(ATS)和欧洲呼吸病学会(ERS)共同制定的,该共识将IIP根据肺脏病理学表现分为7大类,即寻常型间质性肺炎(UIP)(对应的临床诊断为特发性肺间质纤维化,IPF)、非特异性间质性肺炎(NSIP)、隐源性机化性肺炎(COP)、脱屑性间质性肺炎(DIP)、呼吸性细致气管炎并间质性肺炎(RB-ILD)、淋巴细胞性间质性肺炎

会议

Mesenchymal stem cells attenuates vascular remodeling in monocrotaline-induced pulmonary hypertensio

Background Intravenous and intratracheal implantation of mesenchymal stem cells (MSCs) may offer ameliorating effects on pulmonary hypertension (PH) induced by monocrotaline (MCT) in rats.

会议

Increased activation of MKK/p38MAPK/NF-κB signaling pathway in aging human lung

Background The p38 MAPK signaling pathway plays a prominent role in the pro-inflammatory cytokines biosynthesis.Our previous studies showed that p38 MAPK is activated in aged murine lungs with a corre

会议

IL-25 alone induces allergen-independent asthma-like airways inflammation in mice

Background IL-25 (also termed as IL-17E), is a special member of IL-17 family, which is closely linked to asthma.It contributes to the pathogenesis of asthma through enhancing expression of IL-4, IL-5

会议

E-cadherin redistribution in bronchial airway epithelial cells in a TDI-induced asthma model and the

E-cadherin contributes critically to the architecture and immunological function of airway epithelium, which plays an essential role in asthma pathogenesis.

会议

Lung stress and strain during mechanical ventilation in dog acute respiratory distress syndrome mode

Background It has not yet reached an agreement over the mechanism of ventilator induced lung injury (VILI), which is commonly attributed to the application of excessive tidal volume (volutrauma), airw

会议

Serum miR-122 levels correlated to the coagulation disorders of severe sepsis patients

Background miR-122 is a serum signature for liver injury and a prognostic predictor for sepsis patients.Sepsis patients with coagulation abnormalities may be a major impact on the outcome.

会议

Protective effect of 5-aza-2'-deoxycytidine treatment on cigarette smoke-induced emphysema/chro

与本文相关的学术论文