【摘 要】
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Background To investigate the effects of different doses of atorvastatin combined with probucol on extent of myocardial injury in patients undergoing percutaneous coronary intervention (PCI) and its p
【机 构】
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Tianjin Chest Hospital,Tianjin 300051,China
【出 处】
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第十二届中国介入心脏病学大会(CIT2014)
论文部分内容阅读
Background To investigate the effects of different doses of atorvastatin combined with probucol on extent of myocardial injury in patients undergoing percutaneous coronary intervention (PCI) and its possible mechanism.Methods 101 cases were enrolled and randomly divided into 3 groups: standard combined treatment group (n=24,atorvastatin 20 mg qn and probucol 500 mg bid),intensively combined treatment group (n=38,atorvastatin 40 mg qn and probucol 500 mg bid,intaking bolus of atorvastatin 40 mg and probucol 500 mg 2 hours before PCI),and intensive atorvastatin therapy group (n=39,atorvastatin 40 mg qn,bolus intaking atorvastatin 40 mg 2 hours before PCI.Blood was drawn before intaking and 24 hours after PCI to measure the serum lipid profile,myocardial necrosis markers (CK,CK-MB and TnI) and serous myeloperoxidase (MPO).
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