【摘 要】
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Previously we have achieved an one-pot tandem Wittig-cyanosilylation sequence,in which the by-product Ph3PO from the Wittig step were internally recycled as indispensable co-catalysts for the followin
【机 构】
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Shanghai Key Laboratory of Green Chemistry and Chemical Processes,School of Chemistry and Molecular
【出 处】
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中国化学会全国第十二届有机合成化学学术研讨会
论文部分内容阅读
Previously we have achieved an one-pot tandem Wittig-cyanosilylation sequence,in which the by-product Ph3PO from the Wittig step were internally recycled as indispensable co-catalysts for the following asymmetric cyanosilylation step.1 As an effort to extend the utility of such an highly atom-economical tandem reaction,we have recently focused on an one-pot protocol for the highly enantioselective synthesis of versatile chiral conjugated dienes and enynes,the key step of which is an unprecedented asymmetric cyanosilylation of α,β,γ,δ-unsaturated enones.
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