The CSU3 protein kinase mediates COP1 phosphorylation and degradation to control COP1-regulated deve

来源 :12th International Conference on Plant Biology Frontiers(第十二 | 被引量 : 0次 | 上传用户：asdxxx123

【摘要】

：

The RING E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENESIS 1 (COP1) is evolutionarily conserved from plants to animals.COP1 regulates multiple developmental p

【作者】

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Fang Lin Dongqing Xu Yan Jiang Magnus Holm Xing Wang Deng

【机构】

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Peking-YaleJointCenterforPlantMolecularGeneticsandAgro-Biotechnology,StateKeyLaboratoryofProteinandP

【出处】

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12th International Conference on Plant Biology Frontiers(第十二

【发表日期】

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2015年4期

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The RING E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENESIS 1 (COP1) is evolutionarily conserved from plants to animals.COP1 regulates multiple developmental processes via its E3 ubiquitin ligase activity both in planta and animals.In mammalian cells, the ataxia telangiectasia mutated protein kinase (ATM) directly targets COP1 for phosphorylation on Ser-387, thereby triggering self-degradation.

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