Histone H2B ubiquitination plays an important role in gene transcription, DNA damage repair, stem cell differentiation and many other cellular processes.
Recent studies on enzymes regulating dynamic N6-methyl-adenosine (m6A) in RNA together with the findings from m6A-methylated RNA immunoprecipitation followed by
The Mediator complex orchestrates multiple transcription factors with the Pol Ⅱ apparatus for precise transcriptional control.However, its interplay with t
Histone deacetylases (HDAC) play a critical role in regulating gene expression and thus are considered to be an important target of anti-neoplastic therapy.
The mammalian protocadherin (Pcdh) α, β, and γ gene clusters provide a striking example of CTCF/cohesin-mediated enhancer/promoter interactions in cell-speci