Polyprodrug Antimicrobials:Remarkable MembraneDamage and Concurrent Drug Release to Combat Antibioti

来源 :第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con | 被引量 : 0次 | 上传用户:guosheng_741
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  The increased threat of antibiotic resistance is urgent for new strategy.Herein,polyprodrug antimicrobials are proposed to mimic antimicrobial peptides appended with concurrent drug release property,exhibiting broad-spectrum antibacterial activity and especially high potency to inhibit methicillin-resistant Staphylococcus aureus(MRSA)without inducing resistance.
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