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Background and Purpose Memory impairment following subcortical stroke are common symptoms that significantly affect the patients quality of life.However,few studies concentrated on the neural mechanisms of verbal short-term memory(VSTM)impairment which may occur earlier and more widely.We aimed to explore the relationship between VSTM and lesion location and volume,investigate whether brain regions correlated with VSTM in chronic subcortical stroke patients differ from healthy controls and compare regional grey matter volume(GMV)among two groups.