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  5. The LALF32-51 peptide as component of HPV therapeutic vaccine circumvents the alum-mediated inhibiti

The LALF32-51 peptide as component of HPV therapeutic vaccine circumvents the alum-mediated inhibiti

来源 :第十四届全国肿瘤生物治疗大会 | 被引量 : 0次 | 上传用户：xinshou2010
【摘 要】
：
Aluminum-containing adjuvants (alum) continue to be the most widely used adjuvants.It is common knowledge that these adjuvants predominantly induce humoral immunity, but some reports also describe the
【作 者】
：
Milaid Granadillo Alain B.Alfonso Maribel G.Vallespi Aileen Batte Yordanka Soria Enma Brown Miladys Limonta Yayrí C.Prieto Laura Varas Isis Torrens 
【机 构】
：
Center for Genetic Engineering and Biotechnology, Department of Cancer, P.O.Box 6162, Cubanacan, Pla
【出 处】
：
第十四届全国肿瘤生物治疗大会
【发表日期】
：
2015年9期
【关键词】
：
Adjuvant Alum Al(OH)3 Fusion protein LALF32-51-E7 
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　　Aluminum-containing adjuvants (alum) continue to be the most widely used adjuvants.It is common knowledge that these adjuvants predominantly induce humoral immunity, but some reports also describe their role combined with IL-12 in the induction of a Th1 immune response.In this study we want to investigate if alum could be an adjuvant to be used as a component of a therapeutic vaccine that require the generation of cell-mediated immunity.
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