2. 您的位置
3. 首页
4. 会议论文
5. Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in at

Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in at

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：jxwdi

【摘 要】

：

We previously reported a novel triptolide(TP)-glucosamine conjugate(TPG)that specifically accumulated in kidneys and protected renal function from acute ischemia/reperfusion(I/R)injury in rats.

【作 者】

：

Yu Fu Qing Lin Tao Gong Xun Sun Zhirong Zhang 

【机 构】

：

Key Laboratory of Drug Targeting and Drug Delivery Systems,Ministry of Education,West China School o

【出 处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

【关键词】

：

triptolide triptolide-glucosamine conjugate acute kidney injury ischemia/reperfu 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　We previously reported a novel triptolide(TP)-glucosamine conjugate(TPG)that specifically accumulated in kidneys and protected renal function from acute ischemia/reperfusion(I/R)injury in rats.

其他文献

Reconstituted high density lipoprotein(rHDL)carriers for cardiovascular drugs delivery

High-density lipoprotein(HDL),a heterogeneous class of plasma lipoproteins,is a dynamic serum protectant against the development of atherosclerosis and the resultant illnesses such as heart disease an

会议

reconstituted high density lipoproteinatherosclerosisanti-atherosclerosis effe

Optimized preparation of lurasidone hydrochloride nanosuspensions by nanoprecipitation based on pH-d

会议

Screening and preparation of tranexamic acid cream

OBJECTIVE To prepare a stable and curative tranexamic acid cream for the treatment of the periocular chloasma with good transdermal efficiency.

会议

ChloasmaTranexamic acidCream

Complex precipitation formed between baicalin and berberine during decoction

Background: As one of the classic medicine couples,Baikal Skullcap Root and Coptis Root have been reported that precipitate was formed during decoction.Yet there is a lack of more systematic studies o

会议

medicine couplebaicalinberberinecomplex precipitationdecoction

Functionalized Nanoscale Bioinspired Particulates Improve Drug Delivery for Cancer Therapy

Poor penetration of therapeutic drugs into tumors is a major challenge in anticancer therapy,resulting in reduced therapeutic efficacy in vivo.The new tumor-penetrating peptide,CRGDK,triggered specifi

会议

Bioinspired particulatesLipoproteinsTumor-penetrating peptideNeuropilin-1Ant

Preparation and Characterization of eutectic mixture of paeonol and menthol

In the last two decades,the application of eutectics in pharmaceutical field has abstracted more interests due to their contribution on improved drug solubility and permeation.

会议

paeonolmentholeutecticenthalpy of fusioninteraction

Diblock-and triblock-copolymer based mixed micelles with high tumor penetration in vitro and in vivo

会议

Effect of different solvent systems on the characteristics for glycyrrhetinic acid-loaded PLGA micro

会议

Comparative study on the properties of nanoemulsion and liposome loaded with lycobetaine for enhance

In the previous report,lycobetaine(LBT)loaded nanoemlusion(NE)was found to increase the bioavailability than free drug.However,it also could be metabolized and eliminated within 10 hours.

会议

lycobetainenanoemulsionliposomecomparative studybioavailability

Sandwich PHBHHx films to sustain release of TP5 peptide

会议