【摘 要】
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Not only the accumulation of mutations but also the inhibition of cell death plays an important role in carcinogenesis.We previously reported that 8-oxoguanine accumulation in nuclear and mitochondria
【机 构】
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Department of Immunobiology and Neuroscience Kyushu University Japan
论文部分内容阅读
Not only the accumulation of mutations but also the inhibition of cell death plays an important role in carcinogenesis.We previously reported that 8-oxoguanine accumulation in nuclear and mitochondrial DNA triggers two distinct cell death pathways through the buildup of single-strand DNA breaks caused by MUTYH,an adenine DNA glycosylase.
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