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5. Histidine switch-mediated metal sites cooperation of the MarR family transcriptional regulator ZitR

Histidine switch-mediated metal sites cooperation of the MarR family transcriptional regulator ZitR

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：w734289467

【摘 要】

：

　　The MarR type Zinc-specific transcriptional regulator ZitR contains two Zn(Ⅱ)-binding sites per dimeric subunit,with Site-1 being the primary Zn(Ⅱ)-sensin

【作 者】

：

Rongfeng Zhu Yanqun Song Haiping Liu Peng R.Chen 

【机 构】

：

DepartmentofChemicalBiology,CollegeofChemistryandMolecularEngineering,PekingUniversity,Beijing100871

【出 处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年9期

【关键词】

：

histidine switch zinc homeostasis allostery transcription factors X-ray crystall 

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论文部分内容阅读

　　The MarR type Zinc-specific transcriptional regulator ZitR contains two Zn(Ⅱ)-binding sites per dimeric subunit,with Site-1 being the primary Zn(Ⅱ)-sensing site while Site-2s physiological role remains elusive.

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