表皮生长因子对食管鳞癌细胞Eca109细胞周期及其调控因子的影响

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：ixunsoo

【摘要】

：

　　目的：目前国内外关于表皮生长因子(EGF)及其受体EGFR对食管癌细胞增殖的影响存有分歧。本研究采用表达EGFR的食管鳞癌细胞系Eca109,经EGF作用后检测细胞周期和细胞周期蛋

【作者】

：

胡为民黎仕娟李倩倩朱红王朝莉

【机构】

：

川北医学院微生物学与免疫学教研室

【出处】

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中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年期

【关键词】

：

表皮生长因子食管鳞癌细胞系 Eca109细胞细胞周期蛋白依赖性激酶抑制因子调控因子及其受体癌细胞增殖 EGFR

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　　目的：目前国内外关于表皮生长因子(EGF)及其受体EGFR对食管癌细胞增殖的影响存有分歧。本研究采用表达EGFR的食管鳞癌细胞系Eca109,经EGF作用后检测细胞周期和细胞周期蛋白依赖性激酶抑制因子(CKI)家族成员p21CIP1/WAF1 (p21)、p27KIP1 (p27)的变化,为进一步探讨EGF及其受体与食管鳞癌发生、发展的关系提供了新的思路。

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表皮生长因子对食管鳞癌细胞Eca109细胞周期及其调控因子的影响

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