Predict chromatin long-range interactions through 1-D information

来源 :2015 Genomics Frontiers Symposium(2015基因组学前沿研讨会) | 被引量 : 0次 | 上传用户:leng159461
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Many enhancers regulate their target genes via long distance interactions.High-throughput experiments like ChIA-PET have been developed to map such interactions between cis-regulatory elements genome-widely.In this study, we integrated multiple types of data in order to reveal the general hidden patterns embedded in the ChIA-PET data.We found characteristic distance features related to promoter-promoter, enhancer-enhancer,and insulator-insulator interactions.
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