Abnormal expression of PTK7 in head and neck squamous cell carcinoma and its function

来源 :11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲 | 被引量 : 0次 | 上传用户:qiansujiao
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Objective: PTK7 is a tyrosine kinase receptor with catalytic activity, playing important function in normal development.Currently, abnormal expression of PTK7 has been found in colon cancer, lung cancer, gastric cancer and acute myeloid leukemia.Our previous study identified it as a specific membrane marker for stem cell enriched spheroid derived from head and neck squamous cell carcinoma, however, up to date, the biologic meaning of PTK7 expression in head and neck cancer and it function are not clearly.
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