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  5. 4-HNE increases intracellular ADMA levels in cultured HUVECs through miR-21-dependent mechanisms

4-HNE increases intracellular ADMA levels in cultured HUVECs through miR-21-dependent mechanisms

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：lichengjing626
【摘 要】
：
Aim: To investigate whether 4-hydroxynonenal (4-HNE) regulates asymmetric dimethylarginine (ADMA) metabolism through affecting the expression of ADMA metabolizing enzymes and the involvement of microR
【作 者】
：
Lei CHEN Ji-peng ZHOU Da-bin KUANG Jie TANG Yuan-jian LI Xiao-ping CHEN 
【机 构】
：
Department of Pharmacology, School of Pharmaceutical Science, Central South University, Changsha 410
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
microRNA 21 (miR-21) dimethylarginine dimethylaminohydrases (DDAH) asymmetric di 
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Aim: To investigate whether 4-hydroxynonenal (4-HNE) regulates asymmetric dimethylarginine (ADMA) metabolism through affecting the expression of ADMA metabolizing enzymes and the involvement of microRNA (miRNA) miR-21 pathway.
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