目的 To confirm the initiation role of basophils in the early phase of allergic airway inflammation,and further explore the potentmolecular mechanismy which basophils initiate Th2 responses,thus leading to allergic airway inflammation.方法 1.The kinetics of numbers of basophils,dendritic cells(DCs)and Th2 cells in mediastinal lymph nodes(MLN)and the changeof molecular expression on basophils were observed in the early phase of asthma,respectively.