【摘 要】
：
Over 60% of ongoing cell therapy interventions utilize autologous and allogeneic adult stem cells,a large proportion of which are based on mesenchymal stem cells (MSCs).Although a precise definition o
【机 构】
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Academic Unit of Musculoskeletal Disease Leeds Institute of Molecular Medicine UK
【出 处】
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中国上海第七届国际新药发明科技年会
论文部分内容阅读
Over 60% of ongoing cell therapy interventions utilize autologous and allogeneic adult stem cells,a large proportion of which are based on mesenchymal stem cells (MSCs).Although a precise definition of MSCs is currently intensely debated and remains to be refined,MSCs are generally accepted as a group of tissue-specific multipotent progenitors responsible for the development,maintenance and physiological repair of bone,cartilage and fat tissues.Culture-expanded MSCs are now used clinically to treat graft-versus-host disease and to induce tissue regeneration in musculoskeletal and cardiovascular disorders.However,clinical outcomes are often inconsistent and unpredictable.
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