IL-6 and p-STAT3 upregulated in tumor-associated macrophages induced by Supernatant of NIH3T3/Src(Y5

来源 :中国细胞生物学学会2013年全国学术大会 | 被引量 : 0次 | 上传用户：chlo16105

【摘要】

：

The tumor microenvironment could induce macrophages differentiation into Tumor-associated macrophages (TAM),which play an important role in the development of tumor inflammation.

【作者】

：

Lechuang Chen Chenfei Hu Qing Xu Kai Ma Mei Liu Hongxia Zhu Ningzhi Xu

【机构】

：

Laboratory of cell and molecular biology,cancer institute & cancer hospital,Chinese academy of medic

【出处】

：

中国细胞生物学学会2013年全国学术大会

【发表日期】

：

2013年12期

【关键词】

：

TAM Src IL-6 p-STAT3

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

The tumor microenvironment could induce macrophages differentiation into Tumor-associated macrophages (TAM),which play an important role in the development of tumor inflammation.

其他文献

Protein conjugation systems of autophagy participate in acrosome biogenesis during spermatogenesis

Acrosome is a specialized organelle which covers the anterior part of sperm nuclear and plays essential role in sperm-egg fusion.Defect of acrosome biogenesis results in severe fertility disorder call

会议

Oxidative Stress Induces Monocyte Necrosis with Enrichment of Cell-bound Albumin and Overexpression

In the present study,monocytes were treated with 5-azacytidine (azacytidine),gossypol or hydrogen peroxide to induce cell death through oxidative stress.A shift from apoptotic to necrotic cell death o

会议

azacytidineproteomicsheat shock proteinsoxidative stressreactive oxygen spec

PAK4激酶介导的SCG10磷酸化参与胃癌细胞转移

SCG10作为微管不稳定因子,主要参与微管稳态的维持和神经元发育,而在肿瘤发生过程中的功能尚无人报道.在本研究中,我们证明了p21活化激酶4(PAK4)介导的SCG10磷酸化通过调节微管的稳态进而促进胃癌细胞的转移.

会议

PAK4SCG10磷酸化胃癌转移

表观遗传调控因子SNF5的抑癌机制研究

染色质重塑复合物SWl/SNF通过调节染色体结构从而控制基因转录、复制以及DNA损伤修复等,进而在干细胞自我复制,组织分化发育,器官形成等基本生命活动过程中发挥至关重要的作用.

会议

表观遗传癌症SNF5EZH2 p53

重组Raf11-147蛋白的制备与功能研究

丝裂原活化蛋白激酶(mitogen-activated protein kinases,MAPK)信号通路(Ras/Raf/MEK/ERK)是细胞内非常重要的信号转导通路,其异常激活或抑制可能引发如阿尔茨海默氏症、前列腺癌等疾病[1].Raf1蛋白激酶是MAPK信号通路中的一个重要的丝氨酸/苏氨酸特异性蛋白激酶.

会议

Rafl1-147RKIP

结肠腺瘤息肉蛋白突变抑制细胞原生纤毛生长的研究

纤毛是一种突出于细胞表面主要由细胞微管组成的亚细胞结构.纤毛的结构和功能异常导致纤毛相关疾病的发生.结肠腺瘤息肉蛋白(Adenomatous polyposis coli,APC)是一个肿瘤抑制因子.APC突变与家族性结肠腺瘤息肉病(Familial adenomatous polyposis,FAP)和Gardner综合征的发生有关.

会议

结肠腺瘤息肉蛋白Gardner综合症突变纤毛

膀胱癌XPC表达缺失参与影响染色体中心体畸变的分子机制研究

细胞基因组DNA不断受到来自环境的各种外源性因素和来自机体的内源性因素损伤,在众多的修复途径中,核苷酸切除修复(NER)在多种损伤类型中发挥作用,被认为是维持细胞遗传稳定性的主要途径之一.

会议

XPC膀胱癌中心体染色体畸变DNA损伤修复

Egr-1 enhances drug resistance of breast cancer by modulating MDR1 expression in a GGPPS-independent

The multidrug resistance 1 (MDR1) gene product P-glycoprotein is an ATP-dependent efflux pump associated with chemotherapy failure in breast cancer.In the present study,we show that paclitaxel induces

会议

multidrug resistancebreast cancerpaclitaxelMAPKEgr-1

Analysis of the possible mechanisms on correlation between TSHR expression and obesity

Our previous data showed that differentiated adipocyte has higher Tshr protein and mRNA expression level than the preadipocyte.

会议

TSHRobesityThyroid hormoneprotein kinase A(PKA)CREBphospho-CREB(p-CREB)

MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation

Craniofacial malformations are common structural birth defects and usually associate with abnormal development of pharyngeal arches.Although some microRNAs (miRNAs) have been found to be implicated in

会议

mir92aNogginBmppharyngeal cartilage

IL-6 and p-STAT3 upregulated in tumor-associated macrophages induced by Supernatant of NIH3T3/Src(Y5

与本文相关的学术论文