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  5. Detection of SNP-SNP Interaction based on Generalized Particle Swarm Optimization Algorithm

Detection of SNP-SNP Interaction based on Generalized Particle Swarm Optimization Algorithm

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：zqnihao920
【摘 要】
：
Background: Most of complex diseases, such as cancer, heart disease, and diabetes, are believed to be mainly caused by epistatic interactions of two single nucleotide polymorphisms (SNPs).Though many
【作 者】
：
马畅翼 尚军亮 李圣君 孙燕 
【机 构】
：
信息科学与工程学院,曲阜师范大学,日照,276826
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
Epistatic Interactions Mutual Information Particle Swarm Optimization 
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　　Background: Most of complex diseases, such as cancer, heart disease, and diabetes, are believed to be mainly caused by epistatic interactions of two single nucleotide polymorphisms (SNPs).Though many works have been done for the detection of SNP-SNP interactions, the algorithmic development is still ongoing due to their mathematical and computational complexities.
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