Purpose: It is too invasive to achieve hemodynamic variables for pulmonary arterial hypertension (PAH) patients by using right heart catheterization (RHC) during multiple clinical follow-ups. The aim of this study was to determine and validate the mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance (PVR) prediction model by using the noninvasive cardiac magnetic resonance (CMR) indices. Methods: Both Derivation Cohort (N=25) and Validation Cohort (N=25) of PAH underwent both CMR and RHC within 1 week. Fast cine and phase-contrast sequences were used to calculate CMR indices, such as ventricular mass index (VMI), Interventricular septum curvature ratio (CR), and positive pulmonary arterial flow (QP) and etc. The gold standard mPAP (mPAPRHC) and PVR (PVRRHC) were measured from RHC. The Derivation Cohort was used to determine the mPAP (mPAP CMR) calculating from CMR indices using the multiple linear regression. Results: The equation to predict mPAP was: mPAPCMR = 28.837VMI-26.479CR-0.201QP+57.021. Then the equation was applied in the Validation Cohort to verify the prediction accuracy using RHC as the gold standard. mPAPCMR correlated linearly with mPAPRHC as mPAPRHC = 0.8055 mPAPCMR + 7.9056 (p < 0.001) with a good correlation coefficient (r2 = 0.6470). Moreover, PVR calculating from CMR (PVRCMR) also correlated well with the PVRRHC both in the Derivation Cohort (r2 = 0.4092) and in the Validation Cohort (r2 = 0.3480). Conclusion: The application of the mPAPCMR and PVRCMR technique could potentially provide a noninvasive method to assess morphology, right ventricle function, and hemodynamics in single CMR examination for PAH patients.