Plant safflower platform has been established for utilizing its unique oleosin fusion technology for recombinant protein accumulation and purification.Recombinant oleosin fusion proteins carried by oilbodies can be use directly as pharmaceuticals for topical applications.We have successfully expressed several fusion proteins such as oleosin-aFGF, oleosin-bFGF and oleosin-KGF2 fusion proteins in both Arabidopsis and safflower plants.Oilbody as a natural storage oil organ can be easily purified from rest materials of seeds with simple centrifugation and its unique properties of oilbody has been demonstrated for skin penetration, secondary boosting and extending half-life of FGFs.Meanwhile, we have carried out some initial experiments on production of monoclonal antibodies in plant bioreactor system.We also explore many potential applications of this technology in personal care, animal health and other non-pharmaceutical industrials.