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内容一 概述二 常用的生物标志物三 缩短QT间期药物风险标志物研究一、概述Electrical impulse in heart药物延长QT间期致心律失常风险Guideline Documents S7A Safety Pharmacology Studies for Human Pharmaceuticals (2001) S7B Nonclinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceutical (2005) E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs (2005)