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目的探讨早期乳腺癌保乳治疗的手术处理方法及近期疗效。方法 2005年6月至2009年10月共收治女性乳腺癌患者276例,对其中Ⅰ~Ⅱ期原发乳腺癌施行保乳手术治疗,手术方式采用乳腺局部肿物扩大切除加同侧腋窝淋巴结清扫术或同侧前哨腋窝淋巴结活检术,术中对肿物进行切缘冰冻快速病理检查,术后患侧乳房接受放射治疗。结果 53例患者成功实施了保乳手术,手术后随访6个月,对保留乳房治疗的满意率达99%,十分满意占90%,与腋窝前哨淋巴结活检术结合进一步降低了患侧上肢淋巴水肿等并发症的发生,提高了患者的生活质量。经随访2~52个月,中位随访17个月,无乳腺局部复发病例,无远处转移及死亡病例。结论Ⅰ~Ⅱ期乳腺癌保乳治疗近期疗效满意,相关手术的处理方法可行,远期疗效有待长期随访观察。
Objective To investigate the surgical treatment and early curative effect of breast-conserving treatment for early breast cancer. Methods From June 2005 to October 2009, a total of 276 women with breast cancer were treated, and breast-conserving surgery was performed on primary breast cancer with stage Ⅰ-Ⅱ. The operation mode was local enlargement and excision of mammary gland with ipsilateral axillary lymph node dissection Surgery or ipsilateral sentinel axillary lymph node biopsy, intraoperative resection of the tumor frozen rapid pathological examination, postoperative ipsilateral breast radiation therapy. Results 53 patients underwent breast-conserving surgery successfully. The patients were followed up for 6 months. The satisfactory rate of breast-conserving therapy was 99% and 90% satisfied. Combined with axillary lymph node biopsy to further reduce the lymphedema of affected upper limbs And other complications, improve the quality of life of patients. After a follow-up of 2 to 52 months, the median follow-up of 17 months, no local recurrence of breast cancer, no distant metastasis and deaths. Conclusions The efficacy of breast-conserving therapy for patients with stage Ⅰ-Ⅱ breast cancer is satisfactory in the short term, and the treatment of related surgery is feasible. Long-term follow-up of long-term follow-up is needed.