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近几十年来,肿瘤的放射治疗获得很大进展,肿瘤病人的5年存活率越来越高。临床放射治疗的原则首先是根治肿瘤,与此同时应最大限度的保护正常组织,特别是一些重要的组织,如脊髓、心脏、肝、肾等实质性脏器。临床治疗中由于多种原因要改变治疗的分次剂量和分次数时应尽量减少实质性脏器的损伤才能达到完满的治疗目的。多年来,许多临床治疗专家,放射生物学家对治疗总剂量,分次数,分次剂量之间的关系进行了很多的探讨。
In recent decades, radiotherapy of tumors has made great progress, and the five-year survival rate of tumor patients is getting higher and higher. The principle of clinical radiation therapy is to cure the tumor first, and at the same time, it should protect the normal tissues to the utmost extent, especially important tissues such as spinal cord, heart, liver and kidney. In clinical treatment, due to multiple reasons, it is necessary to change the sub-dose and the number of sub-times of treatment to minimize the damage of substantial organs in order to achieve the full purpose of treatment. Over the years, many clinical treatment specialists, radiobiologists, have conducted extensive discussions on the relationship between total doses, fractions, and fractional doses.