本文应用姊妹染色单体交换为指标,对13名服用1号避孕药妇女和13名未用药对照妇女的人流胚胎细胞进行了检测。服药组 SCE 频率/细胞为9.52±1.03,对照组为8.35±0.51(P>0.10)。结果表明,服药期间怀孕或停药3月内怀孕,1号避孕药在临床剂量范围内,不引起胚胎细胞SCE 明显增高,未测到对 DNA 有损伤作用。 In this paper, sister chromatid exchange was used as an indicator to detect the human embryonic cells from 13 women who took birth control pill 1 and 13 women who did not use medication. The frequency of SCE / cell in the medication group was 9.52 ± 1.03 and that in the control group was 8.35 ± 0.51 (P> 0.10). The results showed that pregnancy or withdrawal within 3 months of medication during pregnancy, 1 contraceptives in the clinical dose range, did not cause significantly increased embryonic SCE cells, DNA damage was not detected.