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为探讨１８Ｆ２脱氧葡萄糖（ＦＤＧ）ＰＥＴ显像在肺部单发肿块（ＳＰＮｓ）性质鉴别和肺癌分期中的价值，对２７例肺癌病人（其中单发癌灶者１１例）和１０例肺部单发良性病变病人进行了１８ＦＦＤＧＰＥＴ显像，用定性法和半定量法进行分析，并与ＣＴ、ＭＲＩ、手术及病理结果进行比较。结果示１１例病理检查证实的恶性ＳＰＮｓ病人肺部均可见局部高ＦＤＧ浓集区，单位重量组织ＦＤＧ摄取量与单位体重ＦＤＧ注射量比值（ＳＵＶ）为５７２±２２３，病变与其周围正常组织ＦＤＧ摄取比值（Ｌ／ＮＵＲ）为４２２±２５７；１６例肺部多发癌灶者局部ＦＤＧ摄取也明显增高（ＳＵＶ为５９４±２８６，Ｌ／ＮＵＲ为４５７±２１０）；１０例良性ＳＰＮｓ中除１例活动期肺结核外，余９例均未见高ＦＤＧ浓集区（ＳＵＶ为０９２±０３６，Ｌ／ＮＵＲ为０８３±０２７），良恶性病变间差异有显著性（ｔ＝４１５～６８８，Ｐ均＜００１）。９例经手术治疗的肺癌病人，术前ＰＥＴ分期结果均与手术分期一致，ＣＴ或ＭＲＩ仅６例与手术分期结果一致。ＰＥＴ还在１１例病人中发现了１７个ＣＴ或ＭＲＩ未能发现的转移灶。结果表明，１８ＦＦＤＧＰＥＴ显像是鉴别肺部单发肿块性?
To investigate the value of 18F2deoxyglucose (FDG) PET imaging in distinguishing the nature of lung neoplasms (SPNs) and lung cancer staging, 27 patients with lung cancer (11 patients with single cancer) and 10 patients Eighteen FFDG PET imaging was performed on patients with single benign pulmonary lesions. The qualitative and semi-quantitative methods were used for analysis and compared with CT, MRI, surgery, and pathology results. The results showed that localized high FDG concentrations were seen in the lungs of 11 patients with malignant SPNs confirmed by pathological examination. The FDG intake per unit weight and the ratio of FDG per unit weight (SUV) were 572±223. The normal tissue FDG uptake ratio (L/NUR) was 4 22 2 57; the local FDG uptake was also significantly higher in 16 cases with multiple lung lesions (SUV was 5 94 ± 2 86, L/NUR was 4 . 57±210); In 10 cases of benign SPNs, except for 1 active pulmonary tuberculosis, no high FDG concentration was found in the remaining 9 cases (SUV was 092±036, L/NUR was 083±). 0 27), the difference between benign and malignant lesions was significant (t = 4 15 6 88, P <0 01). Nine cases of lung cancer patients treated by surgery had preoperative PET staging results consistent with surgical staging. Only 6 of CT or MRI were consistent with surgical staging results. PET also found 17 metastases that could not be found on CT or MRI in 11 patients. The results show that 18F-FDG PET imaging is to identify the single lump in the lungs?