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用ＴＣＤ脑血流分析技术对丛集性头痛患者丛集期之无头痛时与头痛时的脑血流速度（ＭＦＶ）进行了研究。患者共１８例，均为男性，平均年龄３０．０±５．６岁。正常对照组也均为男性，平均年龄３２．８±９．９岁。以ＴＣＤ测定了颅内双侧ＭＣＡ、ＡＣＡ、ＰＣＡ以及ＢＡ的ＭＦＶ。结果发现：（１）无头痛时，患者诸动脉之ＭＦＶ与正常对照组比较均无显著差异；（２）头痛时，其痛侧ＭＣＡ之ＭＦＶ与非头痛侧的ＭＦＶ比较显著升高（Ｐ＜０．０１），ＡＣＡ则相反，即显著降低（Ｐ＜０．０１）；头痛时，头痛侧与该侧非头痛时比较，头痛时ＭＣＡ的ＭＦＶ显著高于非头痛时（Ｐ＜０．０１），而ＡＣＡ则相反（Ｐ＜０．０１）。结果表明：丛集性头痛在丛集期头痛时颈内动脉系统之主要分支确有血管收缩，也有扩张的表现。并对其发病机理进行了探讨。
Cerebral blood flow velocity (MFV) during headache-free and group-headache-free cluster headache was studied using TCD cerebral blood flow analysis. A total of 18 patients were male, with an average age of 30.0 ± 5.6 years. The normal control group are also men, with an average age of 32.8 ± 9.9 years. The MFV of intracranial bilateral MCA, ACA, PCA and BA were measured by TCD. The results showed that: (1) There was no significant difference in the MFV of arteries between the two groups when there was no headache; (2) The MFV of MCA in the pain side was significantly higher than that of the non-headache side (P < (P <0.01); while the headache, the MFV of MCA in headache was significantly higher than that in non-headache (P <0.01) ), While ACA was the opposite (P <0.01). The results showed that: cluster headache during cluster headache when the main branch of the internal carotid artery system has vasoconstriction, but also the performance of expansion. And its pathogenesis was discussed.