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目的:探讨纳洛酮治疗急性酒精中毒患者的临床疗效。方法:将符合纳入标准的我院急诊科2015年1月至12月收治的急性酒精中毒患者75例例,随机分为对照组38例和观察组37例,对照组给予补液、吸氧、利尿和心电监护等常规治疗,观察组同时静滴纳洛酮。结果:观察组患者经治疗后清醒时间和症状消失时间均快于对照组,差异均有统计学意义(P<0.05);观察组患者经治疗后TAC和CAT均有明显提升,与治疗前相比差异均有统计学意义(P<0.05);治疗后两组组间比较,观察组的TAC和CAT均有高于对照组,差异均有统计学意义(P<0.05)。结论:纳洛酮能加快急性酒精中毒患者的恢复,提高临床疗效,值得临床应用。
Objective: To investigate the clinical efficacy of naloxone in patients with acute alcoholism. Methods: A total of 75 patients with acute alcoholism admitted to our emergency department from January 2015 to December 2015 were randomly divided into control group (n = 38) and observation group (n = 37). Control group was given rehydration, And ECG custody and other conventional treatment, observation group intravenously naloxone at the same time. Results: The recovery time and symptom disappearance time of the observation group were faster than those of the control group (P <0.05). The TAC and CAT of the observation group were significantly improved after treatment, (P <0.05). After treatment, TAC and CAT in observation group were higher than those in control group, the differences were statistically significant (P <0.05). Conclusion: Naloxone can accelerate the recovery of patients with acute alcoholism and improve clinical efficacy, which is worthy of clinical application.