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作者观察了143例慢性淋巴细胞白血病(简称慢淋)患者周围血淋巴细胞的脱氢酶活性,并以30例健康人作对照。健康人淋巴细胞的脱氢酶活性如下:乳酸脱氢酶(ЛДГ)为21.6±0.39,苹果酸脱氢酶(МДГ)为17.3±0.29,琥珀酸脱氢酶(СДГ)为19.7±0.31,α-甘油磷酸脱氢酶(α-ГФДГ)为15.3±0.14。根据慢淋患者的病情,作者将143例患者分为5组:第1组,15例,患者年龄47~73岁,为疾病的开始期,至诊断时病程为几个月~11年,患者未得到过任何特殊治疗。检查时患者一般情况良好,不需治疗。该组中8例有中度淋巴结肿大及肝脾肿大。所有患者红细胞及血小板数均在正常范围,淋巴细胞占40
The authors observed the dehydrogenase activity of peripheral blood lymphocytes in 143 patients with chronic lymphocytic leukemia (CLL), and 30 healthy people as controls. The dehydrogenase activity of lymphocytes in healthy human was as follows: lactate dehydrogenase (ЛДГ) 21.6 ± 0.39, malate dehydrogenase МДГ 17.3 ± 0.29, succinate dehydrogenase СДГ 19.7 ± 0.31, α - Glyphosate dehydrogenase (α-ГФДГ) is 15.3 ± 0.14. According to the condition of patients with chronic lymphocytic leukemia, 143 patients were divided into 5 groups: Group 1, 15 cases, patients aged 47 to 73 years, the beginning of the disease, to the duration of the diagnosis of several months to 11 years, patients Did not get any special treatment. The patient is generally well tested and does not need treatment. Eight cases in this group had moderate lymphadenopathy and hepatosplenomegaly. All patients with red blood cells and platelets in the normal range, lymphocytes accounted for 40