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Avbaprostil系前列腺素E_2(PGE_2)衍生物,在各种实验模型中对消化性溃疡的疗效强于PGE_2。对21例胃溃疡和17例十二指肠溃疡患者,使用本品后,研究其临床效果。1粒胶囊含本品20μg,每日3次,饭后及睡前各1粒胶囊。通常胃溃疡用药8周,十二指肠溃疡用药6周。结果,以内窥镜判定治愈率胃溃疡为66.7%,十二指肠溃疡62.5%。主客观症状总改善率为“中等改善”以上的胃溃疡80.0%,十二指肠溃疡82.4%。一般来说,
Avbaprostil, a prostaglandin E 2 (PGE 2) derivative, is more potent for peptic ulcer in various experimental models than PGE 2. 21 cases of gastric ulcer and 17 cases of duodenal ulcer patients, after using this product, to study the clinical effect. 1 capsule contains the product 20μg, 3 times a day, 1 capsule after meals and before going to bed. Usually gastric ulcer treatment for 8 weeks, duodenal ulcer medication for 6 weeks. Results, the endoscopic cure rate of gastric ulcer was 66.7%, duodenal ulcer 62.5%. The total objective and subjective symptom improvement rates were 80.0% for gastric ulcer above “moderate improvement” and 82.4% for duodenal ulcer. In general,