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目的：探讨小儿肺炎对肾功能的影响。方法：采用放射免疫法检测了１１６例小儿肺炎急性期血、尿β２－微球蛋白（β２－ＭＧ）含量。结果：血（β２－ＭＧ）含量轻症肺炎组与正常对照组间无明显差异，重症肺炎组明显高于对照组和轻症肺炎组（Ｐ＜０．０５，Ｐ＜０．００１）。尿β２－含量轻症、重症肺炎组与正常对照组间均无明显差异。结论：重症肺炎可伴有肾小球功能损伤。此法灵敏、简便，可作为小儿早期肾功能评估的检测方法
Objective: To investigate the effect of pneumonia on renal function in children. Methods: The blood and urinary β2-microglobulin (β2-MG) levels in 116 children with acute pneumonia were detected by radioimmunoassay. Results: Serum β2-MG levels in patients with mild pneumonia and normal controls were not significantly different. Severe pneumonia was significantly higher than those in control group and mild pneumonia group (P <0.05, P <0.001). Urine β2-content of mild, severe pneumonia group and normal control group no significant difference. Conclusion: Severe pneumonia may be associated with glomerular dysfunction. Sensitive to this method is simple, can be used as a detection method for early renal function in children