长期电刺激引起的机体紊乱

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Objective To create an experimental model of IS intra vitam as well as post mortem assessment of the effect of LESS on the organism.Method The experiment was conducted on 10 rabbit males in developing stage (age 3.5 months). The animals were divided into two groups (n = 5): I in which long timed lateral electric surface stimulation (LESS lt) was applied for 9 h daily during 3 months, II control group, in which rabbits were not stimulated. Growing animals were used so that the investigations would correspond to clinical practice in which adolescents were treated for scoliosis. LESS was performed with SCOL 2, a Polish stimulator, which was placed to the right of the spine, at Th3 Th8 height, 2~ 3 cm below pectoral vertebrae. After 3 months the rabbits were sacrificed,and detailed macroscopic examination was performed.Results LESS statistically significant disturbs growth rate in terms of body mass gains. Individual body mass in this group amounted to 2100 g at the beginning of the experiment, and to 2320 g in the end. Post mortem investigation of LESS lt animals revealed congestion of liver and kidneys, and considerable enlargement of suprarenes.The observed disorders of examined rabbit behaviour in LESS lt group, as well as lesion of suprarenes, suggest stress reaction related to therapy based on this kind of LESS.Conclusions Long timed LESS induced statistically significant disorders of body mass gains in growing rabbits. Long timed LESS was clearly a stressor for the animals.
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