论文部分内容阅读
婴儿肝炎综合征1438例,初诊年龄2～3月龄。首次检测乙型肝炎病毒血清标记(HBVM)获阳性203例(14.25%),阴性者1235例。对首次检测H-BVM 阳性者203例中150例与阴性者601例进行随访,其结果持续阳性者39/150例(26%),阴转阳性者86/601例(14.30%),共获阳性289例(20.10%)。阳转阴者111/150例(74%)。无论是阳转还是阴转者有90%是出现在5月龄内,提示围生期产道感染较宫内增多属一过性感染。HBVM 单项阳性251例(86.85%),二项以上阳性38例(13.14%)。单项阳性为抗HBc 居首(55.7%),依次HBeAg(10.03%),HBsAg(6.57%)。抗-HBc 阳性可能为胎传.对婴儿乙肝HBVM 远期随访有利于婴儿乙肝防治。
1438 cases of infant hepatitis syndrome, initial diagnosis of age 2 to 3 months of age. The first test positive for hepatitis B virus (HBVM) was positive in 203 cases (14.25%), negative in 1235 cases. Of the 203 patients with H-BVM positive for the first time, 150 patients were negative and 601 patients were negative. Follow-up was found in 39/150 (26%) patients with persistent positive results and 86/601 (14.30%) patients with positive negative results. Positive 289 cases (20.10%). 111/150 (74%) with negative conversion. Whether it is positive or negative, 90% of those who appear in the 5-month-old, suggesting that perinatal infection than intrauterine growth is a transient infection. 251 cases (86.85%) were positive for HBVM, and 38 cases (13.14%) were positive for two or more. Single positive for anti-HBc (55.7%), followed by HBeAg (10.03%), HBsAg (6.57%). Anti-HBc positive may be fetal. The long-term follow-up of infant hepatitis B HBVM is conducive to the prevention and treatment of hepatitis B in infants.