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目的:分析研究妊娠急性脂肪肝的临床表现以及治疗方法。方法:随机抽取2006年3月~2014年3月本院接诊的10例妊娠急性脂肪肝患者作为研究对象,对所有患者的临床诊治资料进行回顾式分析。结果:绝大多数患者均在怀孕晚期出现厌食、恶心、呕吐、黄疸以及上腹部不适等症状,其中经阴道分娩6例(双胎1例),产妇死亡3例,新生儿死亡4例;行剖宫产终止妊娠4例,产妇死亡1例,无新生儿死亡。结论:根据实验室检查结果以及患者的早期临床表现对患者进行早诊断早治疗,而依据产妇具体情况选择终止妊娠时机是提高妊娠急性脂肪肝患者以及胎儿生存几率的重要途径。
Objective: To analyze the clinical manifestations and treatment of acute fatty liver in pregnancy. Methods: Ten patients with acute fatty liver of pregnancy who were admitted to our hospital from March 2006 to March 2014 were randomly selected as the research object, and the clinical diagnosis and treatment data of all patients were retrospectively analyzed. Results: Most patients experienced symptoms of anorexia, nausea, vomiting, jaundice and upper abdominal discomfort in late pregnancy, including 6 cases of vaginal delivery (1 case of twins), 3 cases of maternal death and 4 cases of neonatal death. Cesarean section termination of pregnancy in 4 cases, maternal death in 1 case, no newborn deaths. Conclusion: According to the results of laboratory tests and early clinical manifestations of patients with early diagnosis and early treatment of patients, and select the timing of termination of pregnancy according to the specific circumstances of maternal pregnancy is an important way to improve patients with fetal fatty liver and fetal survival probability.