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Cultivation of an endophytic fungus Aspergillus niger EN-13 that was isolated from the inner tissue of the marine brown alga Colpomenia sinuosa resulted in the characterization of a new naphthoquinoneimine derivative,namely,5,7-dihydroxy-2-[1-(4- methoxy-6-oxo-6H-pyran-2-yl)-2-phenylethylamino]-[1,4]naphthoquinone.The structure of the new compound was established on the basis of various NMR spectroscopic analyses including 2D NMR techniques,EI-MS,and HR-ESI-MS.This compound displayed moderate antifungal activity.
Cultivation of an endophytic fungus Aspergillus niger EN-13 that was isolated from the inner tissue of the marine brown alga Colpomenia sinuosa resulted in the characterization of a new naphthoquinoneimine derivative, namely, 5,7-dihydroxy-2- [1- (4- methoxy-6- oxo-6H-pyran-2-yl) -2-phenylethylamino] - [1,4] naphthoquinone.The structure of the new compound was established on the basis of various NMR spectroscopic analyzes including 2D NMR techniques, EI- MS, and HR-ESI-MS. This compound showed moderate antifungal activity.