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目的探讨使用一次性吸痰管连接一次性输液器组成的保留灌肠装置在治疗老年患者抗生素相关性腹泻(ADD)中的效果。方法选取2015年1月至2015年5月入住北京积水潭医院且出现ADD的老年患者62例,采用完全随机分组法分为观察组与对照组,各31例。对照组采取传统保留灌肠法,观察组采用自制的一次性吸痰管连接一次性输液器进行保留灌肠,观察两组患者的耐受性、药液保留时间(药液保留时间大于1 h或小于1 h的例数)并计算肠药液外流率。结果观察组患者耐受性优28例,良3例,差0;对照组耐受性为17例,良10例,差4例,观察组耐受性明显优于对照组,差异有统计学意义(χ2=10.46,P<0.05);灌肠药液保留时间≥1 h的观察组28例,对照组7例,两组比较差异有统计学意义(χ2=28.93,P<0.05);观察组灌肠药液外流率为9.67%(3/31),对照组外流率为58.06%(18/31),观察组灌肠药液外流率明显少于对照组,差异有统计学意义(χ2=16.2、P<0.05)。结论一次性输液器连接一次性吸痰管保留灌肠治疗老年ADD,患者耐受性高,药液保留时间延长,肠液外流率降低,提高疗效,值得临床推广使用。
Objective To explore the effect of using disposable suction tube to connect a disposable infusion set in the treatment of antibiotic-associated diarrhea (ADD) in elderly patients. Methods Sixty-two elderly patients with ADD who were admitted to Beijing Jishuitan Hospital from January 2015 to May 2015 were randomly divided into observation group and control group with 31 cases in each group. In the control group, the traditional retention enema was adopted. The observation group received a one-time infusion set-up with a disposable infusion tube for retention enema. The tolerance of the two groups of patients was observed. The retention time of the drug solution (liquid retention time greater than 1 h or less 1 h cases) and calculate the intestinal fluid efflux rate. Results The observation group patients were excellent in tolerance to 28 cases, good in 3 cases, poor 0; the control group was tolerated in 17 cases, good in 10 cases and poor in 4 cases, the observation group was significantly better than the control group, the difference was statistically significant (Χ2 = 10.46, P <0.05). There were 28 cases in the observation group and 7 cases in the control group, the difference was statistically significant between the two groups (χ2 = 28.93, P <0.05) The efflux rate of enema was 9.67% (3/31) and that of control group was 58.06% (18/31). The efflux rate of enema in observation group was significantly less than that of control group (χ2 = 16.2, P <0.05). Conclusions Disposable infusion tube connected with disposable suction tube to retain enema for the treatment of elderly patients with ADD, patients with high tolerance, prolonged retention of fluid, intestinal fluid efflux rate decreased to improve the efficacy of deserved clinical use.