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1965年Rowe氏等发现一种新的骨髓瘤蛋白,证实具有免疫球蛋白固有的重链(S链)和K型(Kappa)或L型(Lambde)的轻链,命名为免疫球蛋白D(IgD)。 1973年Rowe氏提出IgD型多发性骨髓瘤起沅于B淋巴细胞释放的膜IgD受体,导致对IgD功能新的研究。由于血清中IgD含量甚微,故IgD多从
In 1965, Rowe et al. Found a new myeloma protein that confirmed the immunoglobulin native heavy chain (S chain) and light chain of Kappa or L-form named as immunoglobulin D ( IgD). In 1973, Rowe’s proposed IgD-type multiple myeloma derived from membranous IgD receptors released by B lymphocytes, leading to a new study of IgD function. Due to the small amount of serum IgD, IgD and more from