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巨幼红细胞性贫血是以形态学特征而命名的一组贫血性疾病。除红细胞外,颗粒细胞、单核细胞及巨核细胞系均有改变,临床上并不少见,文献上亦有报告。我院自1964年6月至1980年6月共收治巨幼红细胞性贫血42例,占同期住院病人总数的0.012%。诊断的主要根据是:①外周血红细胞数与血红蛋白均明显低于正常;②骨髓涂片检查出现巨幼红细胞,而原始粒细胞不增多;③叶酸和维生素 B_(12)治疗有显著疗效。本病经过系统治疗及生活指导和加强膳食调理,42例均治愈。
Megaloblastic anemia is a group of anemic diseases named after morphological features. In addition to red blood cells, granulosa cells, monocytes and megakaryocyte lines have changed, clinically not uncommon, there are reports in the literature. Our hospital from June 1964 to June 1980 were treated 42 cases of megaloblastic anemia, accounting for the same period the total number of inpatients 0.012%. The main basis of diagnosis is: ① the number of peripheral blood red blood cells and hemoglobin were significantly lower than normal; ② bone marrow smear showed megaloblastic cells, while the original granulocytes did not increase; ③ folic acid and vitamin B_ (12) treatment has a significant effect. The disease after systematic treatment and life guidance and strengthening diet, 42 cases were cured.