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对Ⅰ、Ⅱ期中、高度恶性非霍奇金淋巴瘤(NHL)的治疗是单纯化疗还是化疗放疗联合应用效果好?本文对此进行对比,结果如下。 病人与方法 病人共401例,均为新诊断的Ⅰ、Ⅱ期NHL,分为化疗组201例,年龄≤60岁103例,>60岁98例,Ⅰ期135例.Ⅱ期66例;乳酸脱氢酶(LDH)正常159例,增高42例,体能状态0或1级193例,2级8例;危险因素(即年龄>60岁、分期、LDH、体能状态)无或1项142例,2项44例,3项14例,4项1例,治疗方案为CHOP,环磷酰胺(CTX)750mg/m~2、阿霉素(ADR)50mg/m~2,长春新碱(VCR)1.4mg/m~2均第1天应用,强的松(P)100mg/m~21～5天用,每疗程间隔21天,共8个疗程。
For the treatment of stage I and II, high-grade malignant non-Hodgkin lymphoma (NHL) is a combination of chemotherapy alone or chemotherapy radiotherapy. This article compares the results, the results are as follows. Patients and Methods A total of 401 patients were newly diagnosed stage I and II NHL, divided into chemotherapy group 201 cases, aged ≤ 60 years 103 cases, >60 years 98 cases, stage I 135 cases, stage II 66 cases; lactic acid Dehydrogenase (LDH) was normal in 159 cases, increased in 42 cases, physical status 0 or 1 in 193 cases, and 2 in 8 cases; risk factors (ie, age> 60 years, staging, LDH, physical status), or 1 case in 142 cases 44 cases in 2 cases, 14 cases in 3 cases, and 1 case in 4 cases. Treatment options were CHOP, cyclophosphamide (CTX) 750 mg/m~2, adriamycin (ADR) 50 mg/m~2, vincristine (VCR ) 1.4mg/m~2 were applied on the first day, prednisone (P) 100mg/m~21~5 days, each treatment interval 21 days, a total of 8 courses.