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本文报道了我院内科肾病组及免疫实验室对126例慢性肾小球肾炎患者进行CIC、CH_(50)和C_3测定的结果,按临床类型和肾功能分组,将所得统计值分别和正常对照组进行了比较。结果表明:肾病型患者或肾功能不全失代偿患者CIC明显升高(P<0.01,0.05>P>0.01)。CH_(50)及C_3在本组患者中均不同程度下降,经t检验,CH_(50)下降以肾病型最为明显,C_3下降则以普通型最为明显。在讨论上述测定的临床意义后,作者认为,对有免疫缺陷或继发性免疫缺陷的肾炎患者,酌情应用免疫兴奋剂是值得重视的。
This article reports the results of CIC, CH_ (50) and C_3 in 126 patients with chronic glomerulonephritis reported by our hospital internal medicine nephropathy group and immune laboratory. According to the clinical type and renal function grouping, the obtained statistics are respectively compared with the normal control Groups were compared. The results showed that patients with renal disease or renal insufficiency patients with CIC was significantly higher (P <0.01, 0.05> P> 0.01). The levels of CH_ (50) and C_3 in all the patients decreased to different extents. The CH_ (50) descended most obviously in nephropathy patients and the C_3 decreased in the normal patients. After discussing the clinical implications of the above assay, the authors concluded that the use of immunostimulants, where appropriate, should be emphasized in patients with nephritis with immunodeficiency or secondary immunodeficiency.