桥本氏甲状腺炎(HT)是一种原发性自体免疫性疾病。从1956年开始,先后在患者血浆中发现甲状腺球蛋白抗体,甲状腺细胞微粒体抗体,胶原抗体,T_4、T_3和 TSH 受体抗体,并在 HT 患者血浆中发现甲状腺兴奋和生长抑制抗体,后者可引起甲低。目前,普遍认为 HT 的发病机制是免疫监测系统受损,由于 T 淋巴细胞“控制器”的功能普遍丧失,促使 T 淋巴细胞对甲状腺抗原产生一系列抗 Hashimoto’s thyroiditis (HT) is a primary autoimmune disease. Since 1956, thyroglobulin antibodies, thyroid cell microsomal antibodies, collagen antibodies, T_4, T_3 and TSH receptor antibodies have been found in the plasma of patients and thyroid stimulating and growth-suppressing antibodies have been found in the plasma of HT patients. The latter A can cause low. At present, it is generally accepted that the pathogenesis of HT is impaired in the immune surveillance system. Due to the general loss of function of T lymphocytes, the “T-lymphocytes” contribute to the generation of a series of anti-thyroid antigens