目的 :考察环丙沙星与维生素C配伍的稳定性。方法 :观察配伍液在不同温度与不同时间的外观、pH值及各组分含量变化和体外抑菌效果。结果 :环丙沙星与维生素C在 5 %GS中配伍后 ,在 37℃以下 ,8h内稳定性良好 ,体外抑菌效果与环丙沙星无显著差异。结论 :在 37℃以下 ,8h内 ,环丙沙星与维生素C可以配伍 Objective: To investigate the stability of compatibility of ciprofloxacin and vitamin C. Methods: To observe the appearance, pH value and the content of each component of the compatibility liquid at different temperatures and different time, and the antibacterial effect in vitro. Results: After the compatibility of ciprofloxacin and vitamin C in 5% GS, the stability was good at 37 ℃ and within 8h. There was no significant difference between the antibacterial activity and ciprofloxacin in vitro. Conclusion: Ciprofloxacin and vitamin C can be compatible within 8 hours and below 37 ℃