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目的探讨心脉隆对急性心肌梗死介入术后心力衰竭患者BNP、IL-6、cTnI指标的影响。方法选取2014年7月—2017年7月行PCI术后出现心力衰竭的AMI患者100例,随机分为对照组和观察组各50例。对照组采用常规治疗,观察组在此基础上使用心脉隆注射液进行治疗。比较两组BNP、IL-6、cTnI指标及临床疗效。计量资料比较采用t检验,计数资料比较采用χ2检验,P<0.05为差异具有统计学意义。结果治疗后两组BNP、IL-6、cTnI均有改善(均P<0.05),且观察组改善效果优于对照组(均P<0.05)。观察组有效率94.0%高于对照组80.0%(P<0.05),差异有统计学意义。结论心脉隆用于急性心肌梗死介入术后心力衰竭患者,可降低肺动脉压与体动脉压,扩张肾血管,增加肾血流量以利尿,抗炎,扩张冠状动脉,增加冠脉流量,抑制心肌损伤。
Objective To investigate the effect of Xinmailong on BNP, IL-6 and cTnI in patients with heart failure after acute myocardial infarction. Methods From July 2014 to July 2017, 100 AMI patients with heart failure after PCI were randomly divided into control group and observation group of 50 cases. In the control group, routine treatment was used. On the basis of this observation group, Xinmailong injection was used for treatment. The indexes of BNP, IL-6 and cTnI in two groups were compared and the clinical curative effect was compared. Measurement data were compared using t test, count data were compared using χ2 test, P <0.05 for the difference was statistically significant. Results After treatment, BNP, IL-6 and cTnI in both groups were improved (all P <0.05), and the improvement in observation group was better than that in control group (all P <0.05). The effective rate of the observation group was 94.0% higher than that of the control group (80.0%, P <0.05), the difference was statistically significant. Conclusion Cardioplegia is used in patients with heart failure after acute myocardial infarction intervention. It can reduce pulmonary arterial pressure and body arterial pressure, expand renal blood vessels, increase renal blood flow to diuretic, anti-inflammatory, dilate coronary arteries, increase coronary flow, inhibit cardiac muscle damage.