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国外报道糖尿病患者使用胰岛素出现过敏的发生率为0.1%~3.0%[1]。随着胰岛素加工、纯化技术的提高及人胰岛素及其类似物的推广应用,胰岛素过敏现象明显减少。成人隐匿性自身免疫糖尿病(LADA)患者对胰岛素过敏的报道比较少,但一旦出现将严重影响治疗。现报告1例对多种胰岛素过敏的LADA患者诊断、脱敏治疗及随访情况,并复习国内外相关报道及文献资料。1临床资料患者女,64岁。主因血糖控制不佳3个月于
Foreign reports of diabetes patients with the incidence of insulin allergy 0.1% to 3.0% [1]. With the insulin processing, purification technology and the promotion of human insulin and its analogues, the phenomenon of insulin allergy decreased significantly. Patients with latent autoimmune diabetes mellitus (LADA) are less likely to report insulin sensitivity but, if present, will seriously affect treatment. Now report a case of a variety of insulin allergy in patients with LADA diagnosis, desensitization treatment and follow-up, and review of relevant reports and literature at home and abroad. 1 clinical data of female patients, 64 years old. Mainly due to poor blood glucose control 3 months at